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Furanoditerpenes from Spongia (Spongia) tubulifera Display Mitochondrial-Mediated Neuroprotective Effects by Targeting Cyclophilin D

[Image: see text] Neuroprotective properties of five previously described furanoditerpenes 1–5, isolated from Spongia (Spongia) tubulifera, were evaluated in an in vitro oxidative stress model in SH-SY5Y cells. Dose–response treatments revealed that 1–5 improved cell survival at nanomolar concentrat...

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Detalles Bibliográficos
Autores principales: Alvariño, Rebeca, Alfonso, Amparo, Pech-Puch, Dawrin, Gegunde, Sandra, Rodríguez, Jaime, Vieytes, Mercedes R., Jiménez, Carlos, Botana, Luis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686139/
https://www.ncbi.nlm.nih.gov/pubmed/35901231
http://dx.doi.org/10.1021/acschemneuro.2c00208