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Furanoditerpenes from Spongia (Spongia) tubulifera Display Mitochondrial-Mediated Neuroprotective Effects by Targeting Cyclophilin D
[Image: see text] Neuroprotective properties of five previously described furanoditerpenes 1–5, isolated from Spongia (Spongia) tubulifera, were evaluated in an in vitro oxidative stress model in SH-SY5Y cells. Dose–response treatments revealed that 1–5 improved cell survival at nanomolar concentrat...
Autores principales: | Alvariño, Rebeca, Alfonso, Amparo, Pech-Puch, Dawrin, Gegunde, Sandra, Rodríguez, Jaime, Vieytes, Mercedes R., Jiménez, Carlos, Botana, Luis M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686139/ https://www.ncbi.nlm.nih.gov/pubmed/35901231 http://dx.doi.org/10.1021/acschemneuro.2c00208 |
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