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High-Throughput Analysis Reveals miRNA Upregulating α-2,6-Sialic Acid through Direct miRNA–mRNA Interactions

[Image: see text] Chemical biology has revealed the importance of sialic acids as a major signal in physiology and disease. The terminal modification α-2,6-sialic acid is controlled by the enzymes ST6GAL1 and ST6GAL2. Dysregulation of this glycan impacts immunological recognition and cancer developm...

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Detalles Bibliográficos
Autores principales: Jame-Chenarboo, Faezeh, Ng, Hoi Hei, Macdonald, Dawn, Mahal, Lara K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686205/
https://www.ncbi.nlm.nih.gov/pubmed/36439307
http://dx.doi.org/10.1021/acscentsci.2c00748