Whole genome DNA and RNA sequencing of whole blood elucidates the genetic architecture of gene expression underlying a wide range of diseases

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To create a scientific resource of expression quantitative trail loci (eQTL), we conducted a genome-wide association study (GWAS) using genotypes obtained from whole genome sequencing (WGS) of DNA and gene expression levels from RNA sequencing (RNA-seq) of whole blood in 2622 participants in Framing...

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Detalles Bibliográficos
Autores principales: Liu, Chunyu, Joehanes, Roby, Ma, Jiantao, Wang, Yuxuan, Sun, Xianbang, Keshawarz, Amena, Sooda, Meera, Huan, Tianxiao, Hwang, Shih-Jen, Bui, Helena, Tejada, Brandon, Munson, Peter J., Demirkale, Cumhur Y., Heard-Costa, Nancy L., Pitsillides, Achilleas N., Peloso, Gina M., Feolo, Michael, Sharopova, Nataliya, Vasan, Ramachandran S., Levy, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686236/
https://www.ncbi.nlm.nih.gov/pubmed/36424512
http://dx.doi.org/10.1038/s41598-022-24611-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686236/
https://www.ncbi.nlm.nih.gov/pubmed/36424512
http://dx.doi.org/10.1038/s41598-022-24611-w

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