Crosslinking of membrane CD13 in human neutrophils mediates phagocytosis and production of reactive oxygen species, neutrophil extracellular traps and proinflammatory cytokines

Aminopeptidase N, or CD13, is a cell membrane ectopeptidase highly expressed in myeloid cells. Through its enzymatic activity, CD13 regulates the activity of several bioactive peptides, such as endorphins and enkephalins, chemotactic peptides like MCP-1 and IL-8, angiotensin III, bradikinin, etc. In...

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Detalles Bibliográficos
Autores principales: Pérez-Figueroa, Erandi, Álvarez-Carrasco, Pablo, Ortega, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686367/
https://www.ncbi.nlm.nih.gov/pubmed/36439182
http://dx.doi.org/10.3389/fimmu.2022.994496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686367/
https://www.ncbi.nlm.nih.gov/pubmed/36439182
http://dx.doi.org/10.3389/fimmu.2022.994496

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