Intratumor heterogeneity is associated with less CD8(+) T cell infiltration and worse survival in patients with small cell lung cancer

PURPOSE: Small cell lung cancer (SCLC) is a heterogeneous malignancy with genetic and phenotypic disparity. However, the association between intratumor heterogeneity (ITH) and immunological features as well as the impact of ITH on prognosis has never been explored in SCLC. Hence, we investigated the...

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Detalles Bibliográficos
Autores principales: Zhang, Chenyue, Li, Zhenzhen, Shang, Xiaoling, Zhao, Chenglong, Wang, Haiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686463/
https://www.ncbi.nlm.nih.gov/pubmed/36422799
http://dx.doi.org/10.1007/s12094-022-03010-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686463/
https://www.ncbi.nlm.nih.gov/pubmed/36422799
http://dx.doi.org/10.1007/s12094-022-03010-7

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