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O-Cyclic Phytosphingosine-1-Phosphate Protects against Motor Dysfunctions and Glial Cell Mediated Neuroinflammation in the Parkinson’s Disease Mouse Models

O-cyclic phytosphingosine-1-phosphate (cPS1P) is a novel and chemically synthesized sphingosine metabolite derived from phytosphingosine-1-phosphate (S1P). This study was undertaken to unveil the potential neuroprotective effects of cPS1P on two different mouse models of Parkinson’s disease (PD). Th...

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Detalles Bibliográficos
Autores principales: Lee, Hyeon Jin, Choe, Kyonghwan, Park, Jun Sung, Khan, Amjad, Kim, Min Woo, Park, Tae Ju, Kim, Myeong Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686509/
https://www.ncbi.nlm.nih.gov/pubmed/36358479
http://dx.doi.org/10.3390/antiox11112107