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Neuroprotective Capability of Narcissoside in 6-OHDA-Exposed Parkinson’s Disease Models through Enhancing the MiR200a/Nrf-2/GSH Axis and Mediating MAPK/Akt Associated Signaling Pathway

We assessed the antioxidant potential of narcissoside from Sambucus nigra flowers (elderflowers) in Parkinson’s disease models in vitro and in vivo. The results showed that narcissoside lessened the 6-hydroxydopamine (6-OHDA)-induced increase in reactive oxygen species (ROS) and apoptosis in SH-SY5Y...

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Detalles Bibliográficos
Autores principales: Fu, Ru-Huei, Tsai, Chia-Wen, Liu, Shih-Ping, Chiu, Shao-Chih, Chen, Yen-Chuan, Chiang, Yu-Ting, Kuo, Yun-Hua, Shyu, Woei-Cherng, Lin, Shinn-Zong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686521/
https://www.ncbi.nlm.nih.gov/pubmed/36358461
http://dx.doi.org/10.3390/antiox11112089