Microglial Hemoxygenase-1 Deletion Reduces Inflammation in the Retina of Old Mice with Tauopathy

Tauopathies such as Alzheimer’s disease are characterized by the accumulation of neurotoxic aggregates of tau protein. With aging and, especially, in Alzheimer’s patients, the inducible enzyme heme oxygenase 1 (HO-1) progressively increases in microglia, causing iron accumulation, neuroinflammation,...

Descripción completa

Detalles Bibliográficos
Autores principales: Fernández-Albarral, José A., Salobrar-García, Elena, Matamoros, José A., Fernández-Mendívil, Cristina, del Sastre, Eric, Chen, Lejing, de Hoz, Rosa, López-Cuenca, Inés, Sánchez-Puebla, Lidia, Ramírez, José M., Salazar, Juan J., Lopez, Manuela G., Ramírez, Ana I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686584/
https://www.ncbi.nlm.nih.gov/pubmed/36358522
http://dx.doi.org/10.3390/antiox11112151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686584/
https://www.ncbi.nlm.nih.gov/pubmed/36358522
http://dx.doi.org/10.3390/antiox11112151

Ejemplares similares