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Microglial Hemoxygenase-1 Deletion Reduces Inflammation in the Retina of Old Mice with Tauopathy

Tauopathies such as Alzheimer’s disease are characterized by the accumulation of neurotoxic aggregates of tau protein. With aging and, especially, in Alzheimer’s patients, the inducible enzyme heme oxygenase 1 (HO-1) progressively increases in microglia, causing iron accumulation, neuroinflammation,...

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Detalles Bibliográficos
Autores principales:	Fernández-Albarral, José A., Salobrar-García, Elena, Matamoros, José A., Fernández-Mendívil, Cristina, del Sastre, Eric, Chen, Lejing, de Hoz, Rosa, López-Cuenca, Inés, Sánchez-Puebla, Lidia, Ramírez, José M., Salazar, Juan J., Lopez, Manuela G., Ramírez, Ana I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686584/ https://www.ncbi.nlm.nih.gov/pubmed/36358522 http://dx.doi.org/10.3390/antiox11112151

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