Population Pharmacokinetics of Orally Administered Clindamycin to Treat Prosthetic Joint Infections: A Prospective Study

A population PK model of clindamycin orally administered to patients with prosthetic joint infections (PJIs) was developed using NONMEM 7.5. Monte-Carlo simulations were run to determine the probability of obtaining bone clindamycin concentrations equal to at least the MIC or four times the MIC for...

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Detalles Bibliográficos
Autores principales: Mimram, Léo, Magréault, Sophie, Kerroumi, Younes, Salmon, Dominique, Kably, Benjamin, Marmor, Simon, Jannot, Anne-Sophie, Jullien, Vincent, Zeller, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686637/
https://www.ncbi.nlm.nih.gov/pubmed/36358117
http://dx.doi.org/10.3390/antibiotics11111462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686637/
https://www.ncbi.nlm.nih.gov/pubmed/36358117
http://dx.doi.org/10.3390/antibiotics11111462

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