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Identification of Heme Oxygenase-1 as a Putative DNA-Binding Protein

Heme oxygenase-1 (HO-1) is a rate-limiting enzyme in degrading heme into biliverdin and iron. HO-1 can also enter the nucleus and regulate gene transcription independent of its enzymatic activity. Whether HO-1 can alter gene expression through direct binding to target DNA remains unclear. Here, we p...

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Detalles Bibliográficos
Autores principales: Scaffa, Alejandro, Tollefson, George A., Yao, Hongwei, Rizal, Salu, Wallace, Joselynn, Oulhen, Nathalie, Carr, Jennifer F., Hegarty, Katy, Uzun, Alper, Dennery, Phyllis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686683/
https://www.ncbi.nlm.nih.gov/pubmed/36358506
http://dx.doi.org/10.3390/antiox11112135