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Synthesis, Biocidal and Antibiofilm Activities of New Isatin–Quinoline Conjugates against Multidrug-Resistant Bacterial Pathogens along with Their In Silico Screening

Isatin–quinoline conjugates 10a–f and 11a–f were assembled by the reaction of N-(bromobutyl) isatin derivatives 3a, b with aminoquinolines 6a–c and their corresponding hydrazinyl 9a–c in good yields. The structures of the resulting conjugates were established by spectroscopic tools and showed data c...

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Detalles Bibliográficos
Autores principales: Elmongy, Elshaymaa I., Ahmed, Abdullah A. S., El Sayed, Ibrahim El Tantawy, Fathy, Ghady, Awad, Hanem M., Salman, Ayah Usama, Hamed, Mohamed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686684/
https://www.ncbi.nlm.nih.gov/pubmed/36358162
http://dx.doi.org/10.3390/antibiotics11111507