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Ishophloroglucin A Ameliorates VEGF-Induced Epithelial-Mesenchymal Transition via VEGFR2 Pathway Inhibition in Microgravity-Stimulated Human Retinal Pigment Epithelial Cells

Microgravity stimulation is associated with retinal pigment epithelial (RPE) cells that transition to mesenchymal cells (EMT), and these pathological changes cause visual impairment. Vascular endothelial growth factor (VEGF) is produced from the RPE and contributes to photoreceptor survival. However...

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Detalles Bibliográficos
Autores principales: Son, Myeongjoo, Ryu, Bomi, Je, Jun-Geon, Jeon, You-Jin, Kim, Dae Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686763/
https://www.ncbi.nlm.nih.gov/pubmed/36358584
http://dx.doi.org/10.3390/antiox11112212