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Investigation of the Possible Protective Effect of N-Acetylcysteine (NAC) against Irinotecan (CPT-11)-Induced Toxicity in Rats

Irinotecan (CPT-11) is a chemotherapeutic agent involved in the treatment regimens for several malignancies such as colorectal cancer. N-acetylcysteine (NAC) is a strong antioxidant and anti-inflammatory agent used in the treatment of several diseases related to oxidative stress and inflammation. Th...

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Detalles Bibliográficos
Autores principales: Gençosman, Sevgi, Ceylanlı, Deniz, Şehirli, Ahmet Özer, Teralı, Kerem, Bölükbaşı, Furkan, Çetinel, Şule, Sayıner, Serkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686802/
https://www.ncbi.nlm.nih.gov/pubmed/36421407
http://dx.doi.org/10.3390/antiox11112219