Genome Mining and Metabolic Profiling Reveal Cytotoxic Cyclodipeptides in Streptomyces hygrospinosus var. Beijingensis

Two new cyclodipeptide (CDP) derivatives (1–2) and another seven known cyclodipeptides (3–9) were isolated from Streptomyces 26D9-414 by the genome mining approach combined with genetic dereplication and the “one strain many compounds” (OSMAC) strategy. The structures of the new CDPs were establishe...

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Detalles Bibliográficos
Autores principales: Zhang, Dashan, Wang, Junbo, Qiao, Yongjian, Lin, Baixin, Deng, Zixin, Kong, Lingxin, You, Delin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686873/
https://www.ncbi.nlm.nih.gov/pubmed/36358118
http://dx.doi.org/10.3390/antibiotics11111463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686873/
https://www.ncbi.nlm.nih.gov/pubmed/36358118
http://dx.doi.org/10.3390/antibiotics11111463

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