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Hedgehog Signalling Contributes to Trauma-Induced Tendon Heterotopic Ossification and Regulates Osteogenesis through Antioxidant Pathway in Tendon-Derived Stem Cells

Heterotopic ossification (HO) is defined as the generation of pathological ectopic bony structures in soft tissues, but the molecular mechanisms of tendon HO are not fully revealed. Hedgehog (Hh) signalling is reportedly critical in hereditary HO. Our study focuses on the role of Hh signalling in th...

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Detalles Bibliográficos
Autores principales: Li, Guanzhi, Deng, Ye, Li, Kaiqun, Liu, Yuchen, Wang, Ling, Wu, Zhiyong, Chen, Chao, Zhang, Kairui, Yu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686894/
https://www.ncbi.nlm.nih.gov/pubmed/36421451
http://dx.doi.org/10.3390/antiox11112265