Targeting Thymidylate Synthase and tRNA-Derived Non-Coding RNAs Improves Therapeutic Sensitivity in Colorectal Cancer

Some colorectal cancer (CRC) patients are resistant to 5-fluorouracil (5-FU), and high expression levels of thymidylate synthase (TS) contribute to this resistance. This study investigated whether quercetin, a representative polyphenol compound, could enhance the effect of 5-FU in CRC cells. Quercet...

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Detalles Bibliográficos
Autores principales: Yang, Changwon, Song, Jisoo, Park, Sunwoo, Ham, Jiyeon, Park, Wonhyoung, Park, Hahyun, An, Garam, Hong, Taeyeon, Kim, Hee Seung, Song, Gwonhwa, Lim, Whasun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686910/
https://www.ncbi.nlm.nih.gov/pubmed/36358529
http://dx.doi.org/10.3390/antiox11112158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686910/
https://www.ncbi.nlm.nih.gov/pubmed/36358529
http://dx.doi.org/10.3390/antiox11112158

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