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NADPH Oxidase 5 (NOX5) Overexpression Promotes Endothelial Dysfunction via Cell Apoptosis, Migration, and Metabolic Alterations in Human Brain Microvascular Endothelial Cells (hCMEC/D3)

NADPH oxidases (NOX) constitute the main reactive oxygen species (ROS) source in blood vessels. An oxidative stress situation due to ROS overproduction can lead into endothelial dysfunction, a molecular mechanism that precedes cardiovascular diseases (CVDs) such as atherosclerosis, myocardial infarc...

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Detalles Bibliográficos
Autores principales: Marqués, Javier, Fernández-Irigoyen, Joaquín, Ainzúa, Elena, Martínez-Azcona, María, Cortés, Adriana, Roncal, Carmen, Orbe, Josune, Santamaría, Enrique, Zalba, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686921/
https://www.ncbi.nlm.nih.gov/pubmed/36358519
http://dx.doi.org/10.3390/antiox11112147