Cargando…
NADPH Oxidase 5 (NOX5) Overexpression Promotes Endothelial Dysfunction via Cell Apoptosis, Migration, and Metabolic Alterations in Human Brain Microvascular Endothelial Cells (hCMEC/D3)
NADPH oxidases (NOX) constitute the main reactive oxygen species (ROS) source in blood vessels. An oxidative stress situation due to ROS overproduction can lead into endothelial dysfunction, a molecular mechanism that precedes cardiovascular diseases (CVDs) such as atherosclerosis, myocardial infarc...
Autores principales: | Marqués, Javier, Fernández-Irigoyen, Joaquín, Ainzúa, Elena, Martínez-Azcona, María, Cortés, Adriana, Roncal, Carmen, Orbe, Josune, Santamaría, Enrique, Zalba, Guillermo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686921/ https://www.ncbi.nlm.nih.gov/pubmed/36358519 http://dx.doi.org/10.3390/antiox11112147 |
Ejemplares similares
-
Induction of Cyclooxygenase-2 by Overexpression of the Human NADPH Oxidase 5 (NOX5) Gene in Aortic Endothelial Cells
por: Marqués, Javier, et al.
Publicado: (2020) -
Cytokine-induced changes in the gene expression profile of a human cerebral microvascular endothelial cell-line, hCMEC/D3
por: Lopez-Ramirez, Miguel Alejandro, et al.
Publicado: (2013) -
Exposure of human cerebral microvascular endothelial cells hCMEC/D3 to laminar shear stress induces vascular protective responses
por: Choublier, Nina, et al.
Publicado: (2022) -
Structure, regulation, and physiological functions of NADPH oxidase 5 (NOX5)
por: García, Jorge G., et al.
Publicado: (2023) -
The endo-lysosomal system of bEnd.3 and hCMEC/D3 brain endothelial cells
por: Toth, Andrea E., et al.
Publicado: (2019)