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Targeting PARK7 Improves Acetaminophen-Induced Acute Liver Injury by Orchestrating Mitochondrial Quality Control and Metabolic Reprogramming
Mitochondrial dysfunction and oxidative stress are considered to be key events in acetaminophen (APAP)-induced acute liver injury. Mitochondrial quality control, including mitophagy and mitochondrial synthesis, can restore mitochondrial homeostasis and thus protect the liver. The role of PARK7, a mi...
Autores principales: | Cai, Jiao, Kong, Deqin, Long, Zi, Liu, Jiangzheng, Liu, Rui, Hai, Chunxu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686963/ https://www.ncbi.nlm.nih.gov/pubmed/36358500 http://dx.doi.org/10.3390/antiox11112128 |
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