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Polymer-Nanodiscs as a Novel Alignment Medium for High-Resolution NMR-Based Structural Studies of Nucleic Acids

Residual dipolar couplings (RDCs) are increasingly used for high-throughput NMR-based structural studies and to provide long-range angular constraints to validate and refine structures of various molecules determined by X-ray crystallography and NMR spectroscopy. RDCs of a given molecule can be meas...

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Detalles Bibliográficos
Autores principales: Krishnarjuna, Bankala, Ravula, Thirupathi, Faison, Edgar M., Tonelli, Marco, Zhang, Qi, Ramamoorthy, Ayyalusamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687133/
https://www.ncbi.nlm.nih.gov/pubmed/36358983
http://dx.doi.org/10.3390/biom12111628