Cisplatin Induces Senescent Lung Cancer Cell-Mediated Stemness Induction via GRP78/Akt-Dependent Mechanism

Cellular senescence is linked with chemotherapy resistance. Based on previous studies, GRP78 is a signal transducer in senescent cells. However, the association between GRP78 and stem cell phenotype remains unknown. Cisplatin treatment was clarified to induce cellular senescence leading to stemness...

Descripción completa

Detalles Bibliográficos
Autores principales: Sriratanasak, Nicharat, Chunhacha, Preedakorn, Ei, Zin Zin, Chanvorachote, Pithi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687146/
https://www.ncbi.nlm.nih.gov/pubmed/36359223
http://dx.doi.org/10.3390/biomedicines10112703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687146/
https://www.ncbi.nlm.nih.gov/pubmed/36359223
http://dx.doi.org/10.3390/biomedicines10112703

Ejemplares similares