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Cisplatin Induces Senescent Lung Cancer Cell-Mediated Stemness Induction via GRP78/Akt-Dependent Mechanism
Cellular senescence is linked with chemotherapy resistance. Based on previous studies, GRP78 is a signal transducer in senescent cells. However, the association between GRP78 and stem cell phenotype remains unknown. Cisplatin treatment was clarified to induce cellular senescence leading to stemness...
Autores principales: | Sriratanasak, Nicharat, Chunhacha, Preedakorn, Ei, Zin Zin, Chanvorachote, Pithi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687146/ https://www.ncbi.nlm.nih.gov/pubmed/36359223 http://dx.doi.org/10.3390/biomedicines10112703 |
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