Cargando…

Beta-Boswellic Acid Reverses 3-Nitropropionic Acid-Induced Molecular, Mitochondrial, and Histopathological Defects in Experimental Rat Model of Huntington’s Disease

Huntington’s disease (HD) is distinguished by a triple repeat of CAG in exon 1, an increase in poly Q in the Htt gene, and a loss of GABAergic medium spiny neurons (MSN) in the striatum and white matter of the cortex. Mitochondrial ETC-complex dysfunctions are involved in the pathogenesis of HD, inc...

Descripción completa

Detalles Bibliográficos
Autores principales: Albekairi, Thamer H., Kamra, Arzoo, Bhardwaj, Sudeep, Mehan, Sidharth, Giri, Aditi, Suri, Manisha, Alshammari, Abdulrahman, Alharbi, Metab, Alasmari, Abdullah F., Narula, Acharan S, Kalfin, Reni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687177/
https://www.ncbi.nlm.nih.gov/pubmed/36359390
http://dx.doi.org/10.3390/biomedicines10112866