Cargando…

Beta-Boswellic Acid Reverses 3-Nitropropionic Acid-Induced Molecular, Mitochondrial, and Histopathological Defects in Experimental Rat Model of Huntington’s Disease

Huntington’s disease (HD) is distinguished by a triple repeat of CAG in exon 1, an increase in poly Q in the Htt gene, and a loss of GABAergic medium spiny neurons (MSN) in the striatum and white matter of the cortex. Mitochondrial ETC-complex dysfunctions are involved in the pathogenesis of HD, inc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Albekairi, Thamer H., Kamra, Arzoo, Bhardwaj, Sudeep, Mehan, Sidharth, Giri, Aditi, Suri, Manisha, Alshammari, Abdulrahman, Alharbi, Metab, Alasmari, Abdullah F., Narula, Acharan S, Kalfin, Reni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687177/ https://www.ncbi.nlm.nih.gov/pubmed/36359390 http://dx.doi.org/10.3390/biomedicines10112866

Ejemplares similares

Forskolin, an Adenylcyclase/cAMP/CREB Signaling Activator Restoring Myelin-Associated Oligodendrocyte Destruction in Experimental Ethidium Bromide Model of Multiple Sclerosis
por: Kapoor, Tarun, et al.
Publicado: (2022)

Renal mitochondrial restoration by gymnemic acid in gentamicin-mediated experimental nephrotoxicity: evidence from serum, kidney and histopathological alterations
por: Gumbar, Shubhangi, et al.
Publicado: (2023)

Activating SIRT-1 Signalling with the Mitochondrial-CoQ10 Activator Solanesol Improves Neurobehavioral and Neurochemical Defects in Ouabain-Induced Experimental Model of Bipolar Disorder
por: Rajkhowa, Bidisha, et al.
Publicado: (2022)

Effect of Natural Adenylcyclase/cAMP/CREB Signalling Activator Forskolin against Intra-Striatal 6-OHDA-Lesioned Parkinson’s Rats: Preventing Mitochondrial, Motor and Histopathological Defects
por: Alharbi, Metab, et al.
Publicado: (2022)

Activation of IGF-1/GLP-1 Signalling via 4-Hydroxyisoleucine Prevents Motor Neuron Impairments in Experimental ALS-Rats Exposed to Methylmercury-Induced Neurotoxicity
por: Shandilya, Ambika, et al.
Publicado: (2022)

Neuroprotective effect of solanesol against 3-nitropropionic acid-induced Huntington's disease-like behavioral, biochemical, and cellular alterations: Restoration of coenzyme-Q10-mediated mitochondrial dysfunction
por: Mehan, Sidharth, et al.
Publicado: (2018)

Effect of alpha-mangostin in the prevention of behavioural and neurochemical defects in methylmercury-induced neurotoxicity in experimental rats
por: Sahu, Rakesh, et al.
Publicado: (2022)

Smo-Shh Agonist Purmorphamine Prevents Neurobehavioral and Neurochemical Defects in 8-OH-DPAT-Induced Experimental Model of Obsessive-Compulsive Disorder
por: Gupta, Ria, et al.
Publicado: (2022)

Korean Red Ginseng Extract Attenuates 3-Nitropropionic Acid-Induced Huntington's-Like Symptoms
por: Jang, Minhee, et al.
Publicado: (2013)

Nrf2/HO-1 Signaling Stimulation through Acetyl-11-Keto-Beta-Boswellic Acid (AKBA) Provides Neuroprotection in Ethidium Bromide-Induced Experimental Model of Multiple Sclerosis
por: Upadhayay, Shubham, et al.
Publicado: (2022)

3-Nitropropionic Acid as a Tool to Study the Mechanisms Involved in Huntington’s Disease: Past, Present and Future
por: Túnez, Isaac, et al.
Publicado: (2010)

Anti-COVID-19 Potential of Ellagic Acid and Polyphenols of Punica granatum L.
por: Alexova, Ralitza, et al.
Publicado: (2023)

Beneficial effect of rice bran extract against 3-nitropropionic acid induced experimental Huntington's disease in rats
por: Kaur, Navneet, et al.
Publicado: (2015)

Guggulsterone Mediated JAK/STAT and PPAR-Gamma Modulation Prevents Neurobehavioral and Neurochemical Abnormalities in Propionic Acid-Induced Experimental Model of Autism
por: Khera, Rishabh, et al.
Publicado: (2022)

Combination of lycopene, quercetin and poloxamer 188 alleviates anxiety and depression in 3-nitropropionic acid-induced Huntington’s disease in rats
por: Jain, Dilpesh, et al.
Publicado: (2014)

Effect of Shorea robusta resin extract in 3-nitropropionic acid-induced Huntington's disease symptoms in Sprague-Dawley rats
por: Patel, Chirag, et al.
Publicado: (2023)

Anti-Huntington’s Effect of Rosiridin via Oxidative Stress/AchE Inhibition and Modulation of Succinate Dehydrogenase, Nitrite, and BDNF Levels against 3-Nitropropionic Acid in Rodents
por: Afzal, Muhammad, et al.
Publicado: (2022)

A Rat Model of Hemidystonia Induced by 3-Nitropropionic Acid
por: Liu, Huan-Guang, et al.
Publicado: (2013)

Diapocynin neuroprotective effects in 3-nitropropionic acid Huntington’s disease model in rats: emphasis on Sirt1/Nrf2 signaling pathway
por: Ibrahim, Weam W., et al.
Publicado: (2022)

Boswellic Acids as Effective Antibacterial Antibiofilm Agents
por: Jaroš, Petr, et al.
Publicado: (2022)

Boswellic acid inhibits expression of acid sphingomyelinase in intestinal cells
por: Zhang, Yao, et al.
Publicado: (2009)

Boswellic Acid Improves Cognitive Function in a Rat Model Through Its Antioxidant Activity: - Neuroprotective effect of Boswellic acid -
por: Ebrahimpour, Saeedeh, et al.
Publicado: (2017)

Raw data of the effects of Chlorogenic acid in 3-Nitropropionic acid induced toxicity and genotoxicity
por: Norberto, Alarcón-Herrera, et al.
Publicado: (2017)

Neuroprotectant Effects of Hibiscetin in 3-Nitropropionic Acid-Induced Huntington’s Disease via Subsiding Oxidative Stress and Modulating Monoamine Neurotransmitters in Rats Brain
por: Mahdi, Wael A., et al.
Publicado: (2023)

Neuroprotective potency of mangiferin against 3-nitropropionic acid induced Huntington’s disease-like symptoms in rats: possible antioxidant and anti-inflammatory mechanisms
por: Lum, Pei Teng, et al.
Publicado: (2023)

Fatal 3-Nitropropionic Acid Poisoning after Consuming Coconut Water
por: Birkelund, Thomas, et al.
Publicado: (2021)

Analysis of 3‐nitropropionic acid in Fabaceae plants by HPLC‐MS/MS
por: Takács, Orsolya, et al.
Publicado: (2022)

Development and optimization of film forming non-pressurized liquid bandage for wound healing by Box-Behnken statistical design
por: Saifullah, Qazi, et al.
Publicado: (2023)

Urease inhibitory activities of β-boswellic acid derivatives
por: Golbabaei, Sanaz, et al.
Publicado: (2013)

Molecular Determinants of the Response of Tumor Cells to Boswellic Acids
por: Eichhorn, Tolga, et al.
Publicado: (2011)

Neuroprotective effect of caffeic acid phenethyl ester in 3-nitropropionic acid-induced striatal neurotoxicity
por: Bak, Jia, et al.
Publicado: (2016)

Measurement of 3-acetyl-11-keto-beta-boswellic acid and 11-keto-beta-boswellic acid in Boswellia serrata Supplements Administered to Dogs
por: Miscioscia, Erin, et al.
Publicado: (2019)

Adenyl cyclase activator forskolin protects against Huntington's disease-like neurodegenerative disorders
por: Mehan, Sidharth, et al.
Publicado: (2017)

3-Nitropropionic Acid Induces Ovarian Oxidative Stress and Impairs Follicle in Mouse
por: Zhang, Jia-Qing, et al.
Publicado: (2014)

Circadian dysfunction in response to in vivo treatment with the mitochondrial toxin 3-nitropropionic acid
por: Kudo, Takashi, et al.
Publicado: (2014)

Neuroprotective effect of silymarin against 3-Nitropropionic acid-induced neurotoxicity in rats
por: Chandolia, Priyanka, et al.
Publicado: (2022)

An Update on Pharmacological Potential of Boswellic Acids against Chronic Diseases
por: Roy, Nand Kishor, et al.
Publicado: (2019)

Boswellic Acids Show In Vitro Activity against Leishmania donovani
por: Greve, Hippolyt L., et al.
Publicado: (2021)

Effect of 3-nitropropionic acid inducing oxidative stress and apoptosis of granulosa cells in geese
por: Kang, Bo, et al.
Publicado: (2018)

Elucidating the effects of heavy metals contamination on vital organ of fish and migratory birds found at fresh water ecosystem
por: Khan, Bushra Nisar, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8l6bav7o6105cic0sk56dn46sk