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FGF9 Promotes Expression of HAS2 in Palatal Elevation via the Wnt/β-Catenin/TCF7L2 Pathway

Background: Fgf9 mutation was found in cleft palate patients. Our previous study indicated that Fgf9 promotes timely elevation of palate by regulating hyaluronic acid (HA) accumulation at embryonic day 13.5 (E13.5). HA is synthesized by hyaluronic acid synthases (HAS) isoforms 1, 2, or 3. However, h...

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Detalles Bibliográficos
Autores principales: Sun, Yidan, Ying, Xiyu, Li, Ruomei, Weng, Mengjia, Shi, Jiajun, Chen, Zhenqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687196/
https://www.ncbi.nlm.nih.gov/pubmed/36358989
http://dx.doi.org/10.3390/biom12111639