LRRK2 and Lipid Pathways: Implications for Parkinson’s Disease

Genetic alterations in the LRRK2 gene, encoding leucine-rich repeat kinase 2, are a common risk factor for Parkinson’s disease. How LRRK2 alterations lead to cell pathology is an area of ongoing investigation, however, multiple lines of evidence suggest a role for LRRK2 in lipid pathways. It is incr...

Descripción completa

Detalles Bibliográficos
Autores principales: Galper, Jasmin, Kim, Woojin S., Dzamko, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687231/
https://www.ncbi.nlm.nih.gov/pubmed/36358947
http://dx.doi.org/10.3390/biom12111597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687231/
https://www.ncbi.nlm.nih.gov/pubmed/36358947
http://dx.doi.org/10.3390/biom12111597

Ejemplares similares