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Gold-Based Metal Drugs as Inhibitors of Coronavirus Proteins: The Inhibition of SARS-CoV-2 Main Protease by Auranofin and Its Analogs

Gold compounds have a long tradition in medicine and offer many opportunities for new therapeutic applications. Herein, we evaluated the lead compound Auranofin and five related gold(I) complexes as possible inhibitors of SARS-CoV-2 Main Protease (SARS-CoV-2 M(pro)), a validated drug target for the...

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Detalles Bibliográficos
Autores principales:	Massai, Lara, Grifagni, Deborah, De Santis, Alessia, Geri, Andrea, Cantini, Francesca, Calderone, Vito, Banci, Lucia, Messori, Luigi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687241/ https://www.ncbi.nlm.nih.gov/pubmed/36421689 http://dx.doi.org/10.3390/biom12111675

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