BDNF Spinal Overexpression after Spinal Cord Injury Partially Protects Soleus Neuromuscular Junction from Disintegration, Increasing VAChT and AChE Transcripts in Soleus but Not Tibialis Anterior Motoneurons

After spinal cord transection (SCT) the interaction between motoneurons (MNs) and muscle is impaired, due to reorganization of the spinal network after a loss of supraspinal inputs. Rats subjected to SCT, treated with intraspinal injection of a AAV-BDNF (brain-derived neurotrophic factor) construct,...

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Detalles Bibliográficos
Autores principales: Głowacka, Anna, Ji, Benjun, Szczepankiewicz, Andrzej Antoni, Skup, Małgorzata, Gajewska-Woźniak, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687248/
https://www.ncbi.nlm.nih.gov/pubmed/36359371
http://dx.doi.org/10.3390/biomedicines10112851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687248/
https://www.ncbi.nlm.nih.gov/pubmed/36359371
http://dx.doi.org/10.3390/biomedicines10112851

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