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BDNF Spinal Overexpression after Spinal Cord Injury Partially Protects Soleus Neuromuscular Junction from Disintegration, Increasing VAChT and AChE Transcripts in Soleus but Not Tibialis Anterior Motoneurons
After spinal cord transection (SCT) the interaction between motoneurons (MNs) and muscle is impaired, due to reorganization of the spinal network after a loss of supraspinal inputs. Rats subjected to SCT, treated with intraspinal injection of a AAV-BDNF (brain-derived neurotrophic factor) construct,...
Autores principales: | Głowacka, Anna, Ji, Benjun, Szczepankiewicz, Andrzej Antoni, Skup, Małgorzata, Gajewska-Woźniak, Olga |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687248/ https://www.ncbi.nlm.nih.gov/pubmed/36359371 http://dx.doi.org/10.3390/biomedicines10112851 |
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