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Setting the Stage for Insulin Granule Dysfunction during Type-1-Diabetes: Is ER Stress the Culprit?

Type-1-diabetes (T1D) is a multifactorial disorder with a global incidence of about 8.4 million individuals in 2021. It is primarily classified as an autoimmune disorder, where the pancreatic β-cells are unable to secrete sufficient insulin. This leads to elevated blood glucose levels (hyperglycemia...

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Detalles Bibliográficos
Autores principales: Makam, Aishwarya A., Biswas, Anusmita, Kothegala, Lakshmi, Gandasi, Nikhil R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687317/
https://www.ncbi.nlm.nih.gov/pubmed/36359215
http://dx.doi.org/10.3390/biomedicines10112695