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Setting the Stage for Insulin Granule Dysfunction during Type-1-Diabetes: Is ER Stress the Culprit?
Type-1-diabetes (T1D) is a multifactorial disorder with a global incidence of about 8.4 million individuals in 2021. It is primarily classified as an autoimmune disorder, where the pancreatic β-cells are unable to secrete sufficient insulin. This leads to elevated blood glucose levels (hyperglycemia...
Autores principales: | Makam, Aishwarya A., Biswas, Anusmita, Kothegala, Lakshmi, Gandasi, Nikhil R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687317/ https://www.ncbi.nlm.nih.gov/pubmed/36359215 http://dx.doi.org/10.3390/biomedicines10112695 |
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