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Metformin Prevents Endothelial Dysfunction in Endometriosis through Downregulation of ET-1 and Upregulation of eNOS

This study aimed to evaluate if the treatment with metformin affects the morphologic structure, endothelial function, angiogenesis, inflammation and oxidation-responsive pathways in the heart of mice with surgically induced endometriosis. B6CBA/F1 mice (n = 37) were divided into four groups; Sham (S...

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Detalles Bibliográficos
Autores principales: Martins, Ana Filipa, Neto, Ana Catarina, Rodrigues, Adriana Raquel, Oliveira, Sandra Marisa, Sousa-Mendes, Cláudia, Leite-Moreira, Adelino, Gouveia, Alexandra Maria, Almeida, Henrique, Neves, Delminda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687337/
https://www.ncbi.nlm.nih.gov/pubmed/36359302
http://dx.doi.org/10.3390/biomedicines10112782