Disease-associated mutations in WDR34 lead to diverse impacts on the assembly and function of dynein-2

The primary cilium is a sensory organelle, receiving signals from the external environment and relaying them into the cell. Mutations in proteins required for transport in the primary cilium result in ciliopathies, a group of genetic disorders that commonly lead to the malformation of organs such as...

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Detalles Bibliográficos
Autores principales: Shak, Caroline, Vuolo, Laura, Uddin, Borhan, Katoh, Yohei, Brown, Tom, Mukhopadhyay, Aakash G., Heesom, Kate, Roberts, Anthony J., Stevenson, Nicola, Nakayama, Kazuhisa, Stephens, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687537/
https://www.ncbi.nlm.nih.gov/pubmed/36268591
http://dx.doi.org/10.1242/jcs.260073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687537/
https://www.ncbi.nlm.nih.gov/pubmed/36268591
http://dx.doi.org/10.1242/jcs.260073

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