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Essential Components of Synthetic Infectious Prion Formation De Novo

Prion diseases are a class of neurodegenerative diseases that are uniquely infectious. Whilst their general replication mechanism is well understood, the components required for the formation and propagation of highly infectious prions are poorly characterized. The protein-only hypothesis posits tha...

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Detalles Bibliográficos
Autores principales: Jack, Kezia, Jackson, Graham S., Bieschke, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687555/
https://www.ncbi.nlm.nih.gov/pubmed/36421708
http://dx.doi.org/10.3390/biom12111694