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Inhibition of SARS-CoV-2 Viral Channel Activity Using FDA-Approved Channel Modulators Independent of Variants

Background: SARS-CoV-2 has undergone mutations, yielding clinically relevant variants. Hypothesis: We hypothesized that in SARS-CoV-2, two highly conserved Orf3a and E channels directly related to the virus replication were a target for the detection and inhibition of the viral replication, independ...

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Detalles Bibliográficos
Autores principales: Yu, Han-Gang, Sizemore, Gina, Martinez, Ivan, Perrotta, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687591/
https://www.ncbi.nlm.nih.gov/pubmed/36421688
http://dx.doi.org/10.3390/biom12111673