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Metabolism of Selenium, Selenocysteine, and Selenoproteins in Ferroptosis in Solid Tumor Cancers

A potential target of precision nutrition in cancer therapeutics is the micronutrient selenium (Se). Se is metabolized and incorporated as the amino acid selenocysteine (Sec) into 25 human selenoproteins, including glutathione peroxidases (GPXs) and thioredoxin reductases (TXNRDs), among others. Bot...

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Detalles Bibliográficos
Autores principales: Shimada, Briana K., Swanson, Sydonie, Toh, Pamela, Seale, Lucia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687593/
https://www.ncbi.nlm.nih.gov/pubmed/36358931
http://dx.doi.org/10.3390/biom12111581