A Pathway Model to Understand the Evolution of Spike Protein Binding to ACE2 in SARS-CoV-2 Variants

After the SARS-CoV-2 Wuhan variant that gave rise to the pandemic, other variants named Delta, Omicron, and Omicron-2 sequentially became prevalent, with mutations spread around the viral genome, including on the spike (S) protein; in order to understand the resultant in gains in infectivity, we int...

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Detalles Bibliográficos
Autores principales: Pipitò, Ludovico, Reynolds, Christopher A., Mobarec, Juan Carlos, Vickery, Owen, Deganutti, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687612/
https://www.ncbi.nlm.nih.gov/pubmed/36358957
http://dx.doi.org/10.3390/biom12111607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687612/
https://www.ncbi.nlm.nih.gov/pubmed/36358957
http://dx.doi.org/10.3390/biom12111607

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