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Potential Application of Recombinant Snake Prothrombin Activator Ecarin in Blood Diagnostics

We describe here the purification and cloning of a codon-optimized form of the snake prothrombin activator ecarin from the saw scaled viper (Echis carinatus) expressed in mammalian cells. Expression of recombinant ecarin (rEcarin) was carried out in human embryonic kidney cells (HEK) cells under con...

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Detalles Bibliográficos
Autores principales: Zhao, Kong-Nan, Masci, Paul, Dimeski, Goce, Johnson, Lambro, Grant, Michael, de Jersey, John, Lavin, Martin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687618/
https://www.ncbi.nlm.nih.gov/pubmed/36421717
http://dx.doi.org/10.3390/biom12111704