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Mechanistic Insights into the Protection Effect of Argonaute–RNA Complex on the HCV Genome

While host miRNA usually plays an antiviral role, the relentless tides of viral evolution have carved out a mechanism to recruit host miRNA as a viral protector. By complementing miR-122 at the 5′ end of the genome, the hepatitis C virus (HCV) gene can form a complex with Argonaute 2 (Ago2) protein...

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Detalles Bibliográficos
Autores principales: Zhuang, Haiming, Ji, Dong, Fan, Jigang, Li, Mingyu, Tao, Ran, Du, Kui, Lu, Shaoyong, Chai, Zongtao, Fan, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687641/
https://www.ncbi.nlm.nih.gov/pubmed/36358979
http://dx.doi.org/10.3390/biom12111631