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Mechanistic Insights into the Protection Effect of Argonaute–RNA Complex on the HCV Genome
While host miRNA usually plays an antiviral role, the relentless tides of viral evolution have carved out a mechanism to recruit host miRNA as a viral protector. By complementing miR-122 at the 5′ end of the genome, the hepatitis C virus (HCV) gene can form a complex with Argonaute 2 (Ago2) protein...
Autores principales: | Zhuang, Haiming, Ji, Dong, Fan, Jigang, Li, Mingyu, Tao, Ran, Du, Kui, Lu, Shaoyong, Chai, Zongtao, Fan, Xiaohua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687641/ https://www.ncbi.nlm.nih.gov/pubmed/36358979 http://dx.doi.org/10.3390/biom12111631 |
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