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Inhibition of Autophagy Promotes the Elimination of Liver Cancer Stem Cells by CD133 Aptamer-Targeted Delivery of Doxorubicin

Doxorubicin is the most frequently used chemotherapeutic agent for the treatment of hepatocellular carcinoma. However, one major obstacle to the effective management of liver cancer is the drug resistance derived from the cancer stem cells. Herein, we employed a CD133 aptamer for targeted delivery o...

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Detalles Bibliográficos
Autores principales: Yin, Wang, Pham, Cuong V., Wang, Tao, Al Shamaileh, Hadi, Chowdhury, Rocky, Patel, Shweta, Li, Yong, Kong, Lingxue, Hou, Yingchu, Zhu, Yimin, Chen, Sunrui, Xu, Huo, Jia, Lee, Duan, Wei, Xiang, Dongxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687680/
https://www.ncbi.nlm.nih.gov/pubmed/36358973
http://dx.doi.org/10.3390/biom12111623