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Impact of N-Acetyl Cysteine (NAC) on Tuberculosis (TB) Patients—A Systematic Review

Sustained TB infection overproduces reactive oxygen species (ROS) as a host defense mechanism. Research shows ROS is destructive to lung tissue. Glutathione (GSH) neutralizes ROS, although it is consumed. NAC is a precursor of GSH synthesis, and administering an appropriate dose of NAC to patients w...

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Detalles Bibliográficos
Autores principales: Mapamba, Daniel Adon, Sauli, Elingarami, Mrema, Lucy, Lalashowi, Julieth, Magombola, David, Buza, Joram, Olomi, Willyhelmina, Wallis, Robert S., Ntinginya, Nyanda Elias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687770/
https://www.ncbi.nlm.nih.gov/pubmed/36421484
http://dx.doi.org/10.3390/antiox11112298