Inter-Site Cooperativity of Calmodulin N-Terminal Domain and Phosphorylation Synergistically Improve the Affinity and Selectivity for Uranyl

Uranyl–protein interactions participate in uranyl trafficking or toxicity to cells. In addition to their qualitative identification, thermodynamic data are needed to predict predominant mechanisms that they mediate in vivo. We previously showed that uranyl can substitute calcium at the canonical EF-...

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Detalles Bibliográficos
Autores principales: Beccia, Maria Rosa, Sauge-Merle, Sandrine, Brémond, Nicolas, Lemaire, David, Henri, Pierre, Battesti, Christine, Guilbaud, Philippe, Crouzy, Serge, Berthomieu, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687771/
https://www.ncbi.nlm.nih.gov/pubmed/36421716
http://dx.doi.org/10.3390/biom12111703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687771/
https://www.ncbi.nlm.nih.gov/pubmed/36421716
http://dx.doi.org/10.3390/biom12111703

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