Chelation Combination—A Strategy to Mitigate the Neurotoxicity of Manganese, Iron, and Copper?

The chelating thiol dimercaptosuccinate (DMSA) and the traditional agent D-penicillamine (PSH) are effective in enhancing the urinary excretion of copper (Cu) and lead (Pb) in poisoned individuals. However, DMSA, PSH, EDTA (ethylenediamine tetraacetate), and deferoxamine (DFOA) are water-soluble age...

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Detalles Bibliográficos
Autores principales: Aaseth, Jan O., Nurchi, Valeria M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687779/
https://www.ncbi.nlm.nih.gov/pubmed/36421727
http://dx.doi.org/10.3390/biom12111713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687779/
https://www.ncbi.nlm.nih.gov/pubmed/36421727
http://dx.doi.org/10.3390/biom12111713

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