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Structural Basis of Sequential and Concerted Cooperativity

Allostery is a property of biological macromolecules featuring cooperative ligand binding and regulation of ligand affinity by effectors. The definition was introduced by Monod and Jacob in 1963, and formally developed as the “concerted model” by Monod, Wyman, and Changeux in 1965. Since its incepti...

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Detalles Bibliográficos
Autores principales: Morea, Veronica, Angelucci, Francesco, Tame, Jeremy R. H., Di Cera, Enrico, Bellelli, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687781/
https://www.ncbi.nlm.nih.gov/pubmed/36359000
http://dx.doi.org/10.3390/biom12111651