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Neuroprotective Effects of Nicotinamide against MPTP-Induced Parkinson’s Disease in Mice: Impact on Oxidative Stress, Neuroinflammation, Nrf2/HO-1 and TLR4 Signaling Pathways

Nicotinamide (NAM) is the amide form of niacin and an important precursor of nicotinamide adenine dinucleotide (NAD), which is needed for energy metabolism and cellular functions. Additionally, it has shown neuroprotective properties in several neurodegenerative diseases. Herein, we sought to invest...

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Detalles Bibliográficos
Autores principales: Rehman, Inayat Ur, Khan, Amjad, Ahmad, Riaz, Choe, Kyonghwan, Park, Hyun Young, Lee, Hyeon Jin, Atiq, Abubakar, Park, Jungsung, Hahm, Jong Ryeal, Kim, Myeong Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687839/
https://www.ncbi.nlm.nih.gov/pubmed/36428497
http://dx.doi.org/10.3390/biomedicines10112929