Comparative Study of Cytotoxic and Membranotropic Properties of Betulinic Acid-F16 Conjugate on Breast Adenocarcinoma Cells (MCF-7) and Primary Human Fibroblasts

The present study evaluates the cytotoxicity of a previously synthesized conjugate of betulinic acid (BA) with the penetrating cation F16 on breast adenocarcinoma (MCF-7) and human fibroblast (HF) cell lines, and also shows the mechanism underlying its membranotropic action. It was confirmed that th...

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Detalles Bibliográficos
Autores principales: Belosludtsev, Konstantin N., Ilzorkina, Anna I., Belosludtseva, Natalia V., Sharapov, Vyacheslav A., Penkov, Nikita V., Serov, Dmitriy A., Karagyaur, Maxim N., Nedopekina, Darya A., Davletshin, Eldar V., Solovieva, Marina E., Spivak, Anna Yu, Kuzmina, Ulyana Sh., Vakhitova, Yulia V., Akatov, Vladimir S., Dubinin, Mikhail V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687851/
https://www.ncbi.nlm.nih.gov/pubmed/36428470
http://dx.doi.org/10.3390/biomedicines10112903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687851/
https://www.ncbi.nlm.nih.gov/pubmed/36428470
http://dx.doi.org/10.3390/biomedicines10112903

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