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Molecular Mechanisms Linking Empagliflozin to Renal Protection in the LLC-PK1 Model of Diabetic Nephropathy

Aims: Chronic diabetes complications, including diabetic nephropathy (DN), frequently result in end-stage renal failure. This study investigated empagliflozin (SGLT2i) effects on collagen synthesis, oxidative stress, cell survival, and protein expression in an LLC-PK1 model of DN. Methods: Combinati...

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Detalles Bibliográficos
Autores principales: Mihaljević, Vjera, Zjalić, Milorad, Kizivat, Tomislav, Omanović Kolarić, Tea, Smolić, Martina, Rođak, Edi, Čović, Marina, Kuna, Lucija, Smolić, Robert, Včev, Aleksandar, Bilić Ćurčić, Ines
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687879/
https://www.ncbi.nlm.nih.gov/pubmed/36428551
http://dx.doi.org/10.3390/biomedicines10112983